Bohs play Shamrock Rovers in one of the stand out games.
Bohemians can go 7 points clear at the top of the SSE Airtricity League Premier Division table tonight with a win in the Dublin Derby.
They travel to Tallaght Stadium to take on rivals Shamrock Rovers from 7:45pm.
At the same time, Derry City can close the gap on the top two as they take on Drogheda United.
Elsewhere, Cork City and St Patrick's Athletic clash at Turner's Cross and Shelbourne host UCD.
In the First Division, leaders Galway United are at home to Waterford,
It's Wexford against Bray Wanderers,
Finn Harps go to Cobh Ramblers,
Treaty United are at home to Athlone Town,
And Kerry FC will bid for their first win of the season against Longford Town.
All of the domestic games this evening kick off at 7.45.
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