Premier and First Division games are down for decision.
There's a full round of fixtures in the SSE Airtricity League Premier Division tonight.
Oriel Park hosts a Louth derby between Dundalk and Drogheda United, while leaders Bohemians go away to UCD.
Derry City entertain St Pat's and Shelbourne host Cork City.
All of those matches kick-off at 7.45, with the meeting of Shamrock Rovers and Sligo Rovers underway from 8.
Galway United bid to extend their winning run to 11 matches tonight.
The First Division leaders face Cobh Ramblers.
Elsewhere, second-placed Waterford make the trip to Bray and Treaty United host Kerry.
Finn Harps take on Longford Town and it's Athlone Town versus Wexford at Lissywollen.

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