The pick of the ties is the meeting of Manchester United & Liverpool.
There's three games down for decision in the Premier League today.
At 2-o'clock Newcastle host Arsenal as they continue their fight to avoid relegation.
A win for Steve Bruce's side would see them go 12 points from the drop zone with four games left to play.
The Gunners won both times the sides met earlier this season.
The main game of the afternoon then is at Old Trafford as Manchester United host rivals Liverpool.
A win for the Reds would see Manchester City win the title.
Kick off in that one is at half-past-4.
Then this evening Tottenham entertain already relegated Sheffield United.