The Six Nations Player of the Championship picked up an injury in training this week and will sit out the game in Galway.
Aoife Wafer has been ruled out of Ireland's second WXV match against Japan on Sunday.
The Six Nations Player of the Championship picked up an injury in training this week and will sit out the game in Galway.
Head coach Scott Bemand has made six changes from last weekend's defeat to the USA.
Neve Jones and Eilís Cahill both come into the front-row, with Brittany Hogan replacing the injured Wafer in the back-row.
Connacht's Aoibheann Reilly is in for her first start in a year at scrum-half, Anna McGann comes in at centre with the fit-again Beibhinn Parsons starting on the wing.

Manchester City Reportedly Found Guilty On Almost All 115 Charges Of Breaking Premier League's Financial Rules
Full Field Of 30 Set For €500,000 Irish Cesarewitch At The Curragh
Premier League, La Liga, Serie A, And Bundesliga State FIFA Is "Not Fit For Purpose"
Scheffler And Burns Make Difference For USA In Opening Day Of Presidents Cup
Friday Morning Sports Update
Republic Of Ireland To Play Kosovo In Nations League Opener
McCabe's Chelsea Get Off To Perfect Start In Champions League
Date Confirmed For Heavyweight Bout Between Joshua And Fury