Jurgen Klopp's side face Southampton at St Mary's.
Liverpool go to Southampton in the Premier League tonight.
Kick off at St Mary's is at 7.45 and Liverpool will be without injured trio Virgil Van Dijk, Mo Salah and Fabinho.
Defeat for Jurgen Klopp's side will confirm Manchester City as Premier League champions.
Arsenal's hopes of qualifying for next season's Champions League are all but over after they lost 2-0 to Newcastle United last night.
It means Tottenham will secure fourth spot and Champions League football if they take a point at relegated Norwich City on the final day of the season.

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