Last-gasp Ronaldo double hands the home side the win.
The Republic of Ireland will now turn their attention to Saturday's World Cup qualifier against Azerbaijan after suffering a heartbreaking 2-1 defeat to Portugal in Faro last night.
Gavin Bazunu saved an early penalty from Cristiano Ronaldo, before John Egan headed Ireland into the lead just before half time.
Stephen Kenny's men held out until the 89th minute when Ronaldo headed home an equaliser.
And then Ronaldo won the game with another header in stoppage time.
The Manchester United forward is now the all time record goalscorer in international football with 111 goals.
Leixlip native and former Leixlip United player, Andrew Omobamidele made his senior debut.
This evening, England are away to Hungary.
Kick off in Budapest is at 7.45.

New Zealand Thrash Australia Again To Hold Onto Bledisloe Cup
Sara Byrne Six Shots Off Lead At Korea Championship
Sligo Rovers Relegated From League Of Ireland Following Heavy Defeat To Shelbourne
Djokovic Suffers Shock Shanghai Masters Exit After Just Winning His 102nd Career Title
Naas Claim Fifth Consecutive Kildare Senior Camogie Title After Thrilling Celbridge Final
Saturday Morning Sports News
Ireland Women's Team Look Forward To A World Cup Play Off After Beating Kazakhstan
Everton's Owners Consider Selling The Club