Andy Farrell has made two changes to the team that started against South Africa as Dan Sheehan replaces Ronan Kelleher and Iain Henderson starts in place of James Ryan.
Jack Conan is named on the Ireland bench the Pool B match against Scotland in Paris on Saturday (8pm).
THe had been sidelined with a foot injury since the start of August but is set to feature at Stade de France.
Iain Henderson gets in ahead of James Ryan in the second row, with the Leinster player starting on the bench. Elsewhere, hooker Dan Sheehan starts with Rónan Kelleher named among the replacements.
The full team is as follows:
Ireland: Hugo Keenan; Mack Hansen, Garry Ringrose, Bundee Aki, James Lowe; Johnny Sexton (capt), Jamison Gibson-Park; Andrew Porter, Dan Sheehan, Tadhg Furlong; Tadhg Beirne, Iain Henderson; Peter O'Mahony, Josh van der Flier, Caelan Doris.
Replacements: Rónan Kelleher, Dave Kilcoyne, Finlay Bealham, James Ryan, Jack Conan, Conor Murray, Jack Crowley, Stuart McCloskey.