Kick-off at Dexcom Stadium at 8pm.
Suncroft's Cian Prendergast returns to captain Connacht for tomorrow's Challenge Cup last-16 clash with the Sharks at Dexcom Stadium.
Head coach Stuart Lancaster has made seven changes from the side that beat the Ospreys, with Bundee Aki and Darragh Murray among the starters.
Sam Gilbert returns from injury at full-back, while Chay Mullins comes in on the wing as Connacht welcome back their Six Nations players.
A sixth consecutive victory would see the province equal their best winning run in a decade.

Tuesday Morning Sports Update
Tottenham Complete Signing Of Midfielder Sandro Tonali
Brazil's Neymar Calls Time On His International Career
Weekend Club GAA Results
Kruger And Kostyuk Get The Action Underway at Wimbledon
Monday Morning Sports Update
Hodges And Glover Share John Deere Classic Lead
Springboks Too Strong As England's Losing Run Continues