Eadestown's Jimmy O'Brien is among the replacements.
Andy Farrell has made three changes to the Ireland team that plays England in the Six Nations on Saturday.
Robbie Henshaw and Ryan Baird come in for injured pair Garry Ringrose and Iain Henderson.
The other switch sees Jamison Gibson-Park make his first start of the competition, with Conor Murray on the bench.
Dan Sheehan keeps his place at hooker, despite suffering a shoulder problem in the win over Scotland, but Ronan Kelleher is ruled out with Rob Herring among the replacements.
Eadestown's Jimmy O'Brien is also on the bench.

Wednesday Morning Sports Update
Claims Ladies Senior Camogie Final Celebrated In Dark Refuted By Kildare LGFA And Kildare GAA
Kildare's Lauren Walsh Finished Third At The Wistron Ladies Open
Tuesday Morning Sports Update
The Girls In Green Are Training In Belgium Ahead Of Tomorrow's Nation League Game
Matty Cash Has Signed A New Contract With Aston Villa
Monday Morning Sports Update
Sunday Morning Sports Update