Curry's claim that he was abused by South Africa's Mbonambi is being investigated by World Rugby.
Elsewhere Marcus Smith comes in at full-back and Henry Arundell is on the wing as two of eight new starters.
Scrum-half Ben Youngs makes his first start of the tournament.
Sam Underhill makes his first appearance of the tournament after being called up to the squad as a replacement for Jack Willis during the pool stages.
Owen Farrell continues at fly-half, while coach Steve Borthwick opts for an all-new front row of Ellis Genge, Theo Dan and Will Stuart.
Ollie Chessum displaces George Martin in the second row to pack down alongside Maro Itoje.

Kildare Reach All-Ireland Minor Semi-Finals With Historic Kerry Win
Irish Pair Miss US Women's Open Cut
Hallgrimsson Satisfied With Ireland Draw Against Canada
Ireland Keep World Cup Dream Alive Ahead Of France Clash
Lowry And McIlroy Suffer Difficult Round 2 At Memorial Tournament
Kildare Camogie Play Roscommon In Championship Clash
Kildare Minors Play Kerry In All-Ireland Quarter-Final
Saturday Morning Sports Update