Curry's claim that he was abused by South Africa's Mbonambi is being investigated by World Rugby.
Elsewhere Marcus Smith comes in at full-back and Henry Arundell is on the wing as two of eight new starters.
Scrum-half Ben Youngs makes his first start of the tournament.
Sam Underhill makes his first appearance of the tournament after being called up to the squad as a replacement for Jack Willis during the pool stages.
Owen Farrell continues at fly-half, while coach Steve Borthwick opts for an all-new front row of Ellis Genge, Theo Dan and Will Stuart.
Ollie Chessum displaces George Martin in the second row to pack down alongside Maro Itoje.

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RDS To Be Known As 'Laya-Arena' After Major Rebrand
Eadestown Tadgh Beirne Included In World's Rugby Team Of The Year
Tuesday Morning Sports Update
Irish Rugby Squad Face Multiple Injuries Woes Following Saturday's Game
Rangers Have Sacked Chief Executive Stewart And Sporting Director Thelwell
Swansea City Confirm New Head Coach Vitor Matos