Curry's claim that he was abused by South Africa's Mbonambi is being investigated by World Rugby.
Elsewhere Marcus Smith comes in at full-back and Henry Arundell is on the wing as two of eight new starters.
Scrum-half Ben Youngs makes his first start of the tournament.
Sam Underhill makes his first appearance of the tournament after being called up to the squad as a replacement for Jack Willis during the pool stages.
Owen Farrell continues at fly-half, while coach Steve Borthwick opts for an all-new front row of Ellis Genge, Theo Dan and Will Stuart.
Ollie Chessum displaces George Martin in the second row to pack down alongside Maro Itoje.

Katie Taylor Remains Hopeful For Her Dream To Fight At Croke Park
Erin King To Captain Ireland
McIlroy Masters Defence Begins This Afternoon
Thursday Morning Sports Update
Grace Davison Breaks Irish Senior Women's 100 Metres Freestyle Record
Flick Braced For Emotional Clash As Barcelona Host Atletico
Wednesday Morning Sports Update
Harry Maguire Signs New Deal With Manchester United