Curry's claim that he was abused by South Africa's Mbonambi is being investigated by World Rugby.
Elsewhere Marcus Smith comes in at full-back and Henry Arundell is on the wing as two of eight new starters.
Scrum-half Ben Youngs makes his first start of the tournament.
Sam Underhill makes his first appearance of the tournament after being called up to the squad as a replacement for Jack Willis during the pool stages.
Owen Farrell continues at fly-half, while coach Steve Borthwick opts for an all-new front row of Ellis Genge, Theo Dan and Will Stuart.
Ollie Chessum displaces George Martin in the second row to pack down alongside Maro Itoje.

Kildare Battle Past Tyrone To Reach All-Ireland Camogie Semi-Finals
Armagh End Kildare's All-Ireland Journey
England's World Cup Last-16 Tie To Go Ahead As Scheduled
Ireland Fight Back To Stun Australia In Sydney Thriller
Cape Verde Exit World Cup After Extra-Time Thriller
Foster Moves Into Contention At Belgian Open
Saturday Morning Sports Update
Kildare Ladies Football Team Announced To Play Armagh In All-Ireland Quarter Final