Curry's claim that he was abused by South Africa's Mbonambi is being investigated by World Rugby.
Elsewhere Marcus Smith comes in at full-back and Henry Arundell is on the wing as two of eight new starters.
Scrum-half Ben Youngs makes his first start of the tournament.
Sam Underhill makes his first appearance of the tournament after being called up to the squad as a replacement for Jack Willis during the pool stages.
Owen Farrell continues at fly-half, while coach Steve Borthwick opts for an all-new front row of Ellis Genge, Theo Dan and Will Stuart.
Ollie Chessum displaces George Martin in the second row to pack down alongside Maro Itoje.
Lossiemouth Has Won The Champion Hurdle On The Opening Day Of The Cheltenham Festival
Niall Scannell Will Retire From Munster Rugby At The End Of The Season
Old Park Star has won the Supreme Novices' Hurdle
Tuesday Morning Sports Update
Ireland And England Will Meet Next February To Kick Off 2027 Six Nations
Tolka Park Stages The Dublin Derby Between Shelbourne And Shamrock Rovers
Conor McGregor Not Included In White House Fight In June
Ireland's Men And Women Hockey Teams Book Their Spot At This Year's World Cup
