Curry's claim that he was abused by South Africa's Mbonambi is being investigated by World Rugby.
Elsewhere Marcus Smith comes in at full-back and Henry Arundell is on the wing as two of eight new starters.
Scrum-half Ben Youngs makes his first start of the tournament.
Sam Underhill makes his first appearance of the tournament after being called up to the squad as a replacement for Jack Willis during the pool stages.
Owen Farrell continues at fly-half, while coach Steve Borthwick opts for an all-new front row of Ellis Genge, Theo Dan and Will Stuart.
Ollie Chessum displaces George Martin in the second row to pack down alongside Maro Itoje.

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Leinster Retain URC Crown With Dominant Final Victory
McIlroy Keeps US Open Hopes Alive As Irish Challenge Narrows
Kildare's Walsh Makes Meijer LPGA Cut
Kildare Ladies Face Tipperary In Crucial Clash
Kildare Minors Fall Just Short Of All-Ireland Final
Saturday Morning Sports Update