Curry's claim that he was abused by South Africa's Mbonambi is being investigated by World Rugby.
Elsewhere Marcus Smith comes in at full-back and Henry Arundell is on the wing as two of eight new starters.
Scrum-half Ben Youngs makes his first start of the tournament.
Sam Underhill makes his first appearance of the tournament after being called up to the squad as a replacement for Jack Willis during the pool stages.
Owen Farrell continues at fly-half, while coach Steve Borthwick opts for an all-new front row of Ellis Genge, Theo Dan and Will Stuart.
Ollie Chessum displaces George Martin in the second row to pack down alongside Maro Itoje.
Kildare Senior Football Team Announced For Tomorrow's O'Byrne Cup Semi-Final
Ulster Head Coach Richie Murphy Makes 10 Changes For Their Game With Cheetahs
Connacht Announce Changes For Their Away Game Against Montpellier
Munster Make 10 Changes For Their Trip To Toulon On Sunday
The Leinster Rugby Team To Take On La Rochelle In The Investec Champions Cup Has Been Named
Friday Morning Sports Update
Arsenal Can Open An Eight Point Lead At The Top Of The Premier League If They Succeed Liverpool Tonight
Lara Gillespie Will Not Attend Next Month's European Track Cycling Championships in Turkey
