James Horan's side will compete in Division One.
Mayo look set to play all of their National Football League matches away from home next year.
It's reported that no games will be held in the county as works are being carried out on the playing surface at MacHale Park.
It's unlikely that any other venue in Mayo would be capable of accommodating the large crowds expected for their Division One fixtures in 2022.
James Horan's side earned promotion back to the top tier earlier this year.

Old Park Star has won the Supreme Novices' Hurdle
Tuesday Morning Sports Update
Ireland And England Will Meet Next February To Kick Off 2027 Six Nations
Tolka Park Stages The Dublin Derby Between Shelbourne And Shamrock Rovers
Conor McGregor Not Included In White House Fight In June
Ireland's Men And Women Hockey Teams Book Their Spot At This Year's World Cup
Ireland To Train Collectively Today Ahead Of Next Saturday's Six Nations Clash
Monday Morning Sports Update