James Horan's side will compete in Division One.
Mayo look set to play all of their National Football League matches away from home next year.
It's reported that no games will be held in the county as works are being carried out on the playing surface at MacHale Park.
It's unlikely that any other venue in Mayo would be capable of accommodating the large crowds expected for their Division One fixtures in 2022.
James Horan's side earned promotion back to the top tier earlier this year.

ROI Under 21 Play Two International Friendlies Next Month
Three Irish Players Picked On Women's Six Nations Team Of The Tournament
Ulster Name Team For Tomorrow's Challenge Cup Final Against Montpellier
GSTAAD Heads Declaration for Saturday’s Tattersalls Irish 2,000 Guineas
Southampton Out Of Championship Play-Off Final After Spying On Rival Sides
Aston Villa Crowned Europa League Champions
Thursday Morning Sports Update
Aston Villa Keep Hopes Alive For Clash Against Freiburg In The Europa League Final Tonight