Darragh Murray and Josh Murphy make their 50th appearances for the province.
Connacht head coach Stuart Lancaster makes three changes from the side that lost to Montpellier last weekend.
Hooker Dave Heffernan, scrum-half Matthew Devine and out-half Jack Carty coming into the side after all three returned from injury.
The second row pairing of Darragh Murray and Josh Murphy make their 50th appearances for the province.
Jack Aungier and Sean Naughton return from injury and are named on the bench.
15. Sam Gilbert (7)
14. Shane Jennings (25)
13. Harry West (5)
12. Cathal Forde (61)
11. Finn Treacy (14)
10. Jack Carty (227)
9. Matthew Devine (26)
1. Billy Bohan (3)
2. Dave Heffernan (227)
3. Sam Illo (38)
4. Darragh Murray (49)
5. Josh Murphy (49)
6. Cian Prendergast (94) (C)
7. Paul Boyle (124)
8. Sean Jansen (36)
16. Dylan Tierney-Martin (65)
17. Denis Buckley (271)
18. Jack Aungier (92)
19. Joe Joyce (45)
20. Sean O’Brien (22)
21. Ben Murphy (25)
22. Sean Naughton (7)
23. Sean Walsh (2)

Tuesday Morning Sports Update
All Ireland Football Championship Opening Round Fixtures Confirmed
Tommy O'Brien Among Injury Doubts For Leinster's Champion Cup Final On Saturday
Monday Morning Sports Update
Sunday Evening Sports Update
Mourinho's Benefica Go Unbeaten but Miss Title
Brave Kildare Fall Short in Leinster Ladies Final
Chelsea Appoint Xabi Alonso as New Manager