She will play alongside sibling Venus in the first round of the women's doubles.
Serena Williams says she "relished" her return to singles tennis, despite defeat to Maya Joint in the first round of Wimbledon last night.
The seven-time champion saved a match point to force a decider last night, but it was the Australian who came out on top on Centre Court.
Williams will play alongside her sister Venus in the first round of the women's doubles tomorrow.
The first major shock came in the men's draw yesterday - fourth seed Ben Shelton lost the fifth-set tiebreak to Finnish qualifier Otto Virtanen.
First up on Centre Court today, world number one Jannik Sinner plays Portugal's Nuno Borges for a place in the third round.
Novak Djokovic is up against former World Number 3 Stefanos Tsitsipas later.
In the women's draw, top seed Aryna Sabalenka faces the American McCartney Kessler on Number 1 Court,
That's followed by seventh seed Coco Gauff against Solana Sierra of Argentina.
Wednesday Morning Sports Update
Thomas Carty To Lead Undercard For Taylor's Homecoming Fight At Croke Park
Williams Returns To Singles Tennis At Wimbledon This Afternoon
Tuesday Morning Sports Update
Venue Confirmed For Must-Win Game Against Tyrone
Enzo Maresca Appointed Successor To Guardiola At Manchester City
Wimbledon Championship Gets Underway This Afternoon
All-Ireland Senior Football Championship Semi-Final Fixtures Announced
