World number one Jon Rahm and Sergio Garcia will face Justin Thomas and Jordan Spieth in the opening match.
The 43rd Ryder Cup between Europe and the United States begins at 1.05 Irish time in Wisconsin.
European skipper Padraig Harrington has rested Shane Lowry for the opening foursomes at Whistling Straits.
World number one Jon Rahm and Sergio Garcia will face Justin Thomas and Jordan Spieth in the opening match.
Paul Casey and Viktor Hovland are to take on Dustin Johnson and Collin Morikawa.
Lee Westwood and Matt Fitzpatrick are up against Brooks Koepka and Daniel Berger.
And Rory McIlroy and Ian Poulter are to play Patrick Cantlay and Xander Schauffele.